EVAg

Variant of the SARS-CoV-2 receptor binding domain (aa 319-591) with mutation E484Q. Recombinant protein expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Variant of the SARS-CoV-2 receptor binding domain (aa 319-591) with mutation E484K. Recombinant protein expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Variant of the SARS-CoV-2 receptor binding domain (aa 319-591) with mutations L452R and N501Y. Recombinant protein expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Variant of the SARS-CoV-2 receptor binding domain (aa 319-591) with mutations E484K and N501Y. Recombinant protein expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Recombinant receptor binding domain (aa 319-591) of SARS-CoV-2 Gamma variant (mutations: K417T, E484K, N501Y) , expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Recombinant receptor binding domain (aa 319-591) of SARS-CoV2 Omicron variant BA.1 (Mutations: G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A,  Q493K, G496S, Q498R, N501Y, Y505H, T547K), expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Recombinant receptor binding domain (aa 319-591) of SARS-CoV2 Delta variant (mutations: L452R, T478K), expressed in Expi293 cells and Streptactin-purified. The protein is equipped with a SpyTag (AHIVMVDAYKPTK) at the C-terminus.

Generation of recombinant chimeric monoclonal antibodies: murine monoclonal antibodies (hybridoma cells or total RNA have to be provided by the end-user) will be sequenced, cloned, recombinantly expressed in Expi293 cells, and purified via protein G. Available backbones for heavy and light chain constant regions are: mouse IgG1, Ig kappa; mouse IgG2a, Ig kappa; rabbit IgG, Ig kappa; human IgG1, Ig kappa; porcine IgG, Ig kappa; and bovine IgG, Ig kappa. Other backbones could possibly also generated uppon request.