Human anti-HCoV-OC43 Spike protein (S2) IgG1, monoclonal antibody (clone BCP002)


EVAg

Produced by
: ERASMUS-MC
Shipping From
: Rotterdam - NL

Product Description

Ref-SKU:
010A-05018
Human monoclonal recombinant IgG1 targeting the S2 domain of HCoV-OC43 Spike domain, as determined by ELISA.
Product Risk Group: 

Information on the related virus

Virus name: 


Unit definition: 
1 vial, ~500 µL, 12,8 µg/mL, 6,4 µg

Upon request

500,00 €
(Cost per access for Academics)

catalogue

biobank

Portal

EVAg

purchase

buy

order

price

cost

shipping

shipment

experiment

research

laboratory

viral

virus

Product type: 
Antibody
Targeted antigen: 
Virus
Antibody type: 
Monoclonal
Antibody purified by affinity: 
Yes
Production system: 
Human HCoV-OC43 Spike specific B-cells were identified through culturing at limiting dilution. Heavy and Light variable sequences were amplified. After amplification the variable regions were cloned into Heavy and Light pFUSEss expression plasmids. The antibody was expressed by co-transfecting 293T cells with both plasmids. Secreted antibody was subsequently affinity purified and concentrated.
Antibody characterization method(s): 
ELISA
Information on characterization: 
The antibody showed reactivity towards HCoV-OC43 S-trimer (Sino Biological; 40607-V08B) and S2 domain (Sino Biological; 40607-V08B1). Antibody showed high affinity for S2 as determined by ELISA.
Specificity documented: 
Yes
Virus host type: 
Antibody specificity: 
This antibody is specific for the S2 domain of spike protein of HCoV-OC43 virus.
Previous Name or Taxonomy: 
Shipping conditions: 
IATA Classification: